C-Peptide
Also known as: Connecting Peptide
A lab marker of the body's own insulin production — used as a Medicare documentation requirement for insulin pump coverage.
C-peptide is a protein released in equal amounts to insulin when the pancreas produces insulin. Because exogenous (injected) insulin does not contain C-peptide, the blood level of C-peptide reflects the body's own insulin production accurately.
For Medicare insulin pump coverage, a C-peptide test below a specific threshold (0.5 ng/mL or below, obtained while the patient's blood glucose is at least 200 mg/dL) is required documentation to establish Type 1 diabetes or similar insulin deficiency. This documentation must be on file at the DME supplier.
C-peptide is also used diagnostically to distinguish Type 1 from Type 2 diabetes, evaluate beta cell function after pancreatic surgery, and investigate hypoglycemia causes.
Frequently asked
What is C-Peptide?
A lab marker of the body's own insulin production — used as a Medicare documentation requirement for insulin pump coverage. C-peptide is a protein released in equal amounts to insulin when the pancreas produces insulin. Because exogenous (injected) insulin does not contain C-peptide, the blood level of C-peptide reflects the body's own insulin production accurately.
How does C-Peptide relate to Medicare coverage?
Medicare Part B covers most durable medical equipment related to C-Peptide. Contact us to verify your specific coverage for related diabetic supplies.
Where can I get diabetic supplies related to C-Peptide in Phoenix?
We deliver Medicare-covered diabetic supplies throughout the Phoenix metro area. Call us or complete the form above to verify your coverage.